Iron(iii)-catalyzed radical α,ß-aminophosphinoylation of styrenes with diphenylphosphine oxides and anilines.

A Fe-catalyzed highly regioselective α,ß-difunctionalization of vinylarenes with diphenylphosphine oxides and anilines is disclosed, in which α,ß-aminophosphinoylation is efficiently and conveniently constructed under mild conditions with good functional compatibility and a broad substrate scope. The control experiments have revealed a radical reaction pathway.

Silver-catalyzed intermolecular amination of fluoroarenes.

A novel highly selective Ag-catalyzed intermolecular amination of fluoroarenes has been developed. This transformation starts from readily available 4-carbonyl fluorobenzene and NaN3 or other nitrogen-source, via amination followed by C-F bond cleavage, thus affording the desired 4-carbonyl arylamine products under mild conditions. The reaction is accelerated using a small amount of water. This pathway is distinct from a previously reported radical amination reaction.